Published December 2000
by R. G. Landes .
|The Physical Object|
|Number of Pages||307|
Get this from a library! Recombinant protease inhibitors in plants. [Dominique Michaud;] -- Table of Contents: 1. Protease/inhibitor interactions in plant-pest systems: a brief overview, 2. Control of Phytophagous insect pests using serine protease inhibitors, 3. Cystatin-based control of. Recombinant Protease Inhibitors in Plants (Biotechnology Intelligence Unit 3) Recombinant Protease Inhibitors in Plants (Biotechnology Intelligence Unit 3) Lalmanach, Gilles edited by Dominique Michaud (Landes Bioscience and , TX, USA), (hbk) ( pages), ISBN 1 8 Owing to the negative effects of chemical pesticides in the . The importance of proteolytic enzymes in plant-pest and plant-pathogen interactions has recently been recognized, and control strategies based on their inhibition with protease inhibitors (PIs) have been developed or proposed to control herbivory insects (), plant parasitic fungi (2, 3), and nematodes ().The various roles of proteases in these organisms and the biochemical pathways affected by Cited by: Stability of Recombinant Proteins in Plants. tubers, roots), by the addition of protease inhibitors (EDTA The aim of this book is to offer background information to students and.
Abstract. We previously described a procedure for the use of plant protease inhibitors as “companion” accessory proteins to prevent unwanted proteolysis of clinically useful recombinant proteins in leaf crude protein extracts (Benchabane et al. Methods Mol Biol –, ).Cited by: 8. 4. Protease Inhibitors with Antimicrobial Activities from Various Plants. Protease inhibitors are ubiquitous in tubers and plant seeds , and are generally believed to act as storage proteins and a defense mechanism .Protease inhibitors control the action of proteases that are indispensable for the growth and development of the by: Plants are known to have many secondary metabolites and phytochemical compounds which are highly explored at biochemical and molecular genetics level and exploited enormously in the human health care sector. However, there are other less explored small molecular weight proteins, which inhibit proteases/proteinases. Plants are good sources of protease inhibitors (PIs) which protect them against Cited by: An interesting, relatively new strategy is to minimize proteolysis by co-expression of a recombinant “companion” protease inhibitor in a transgenic plant or in plants transiently expressing recombinant proteins. 18 Recombinant protease inhibitors have been previously applied as anti-digestive compounds for crop protection against insect Cited by:
Intended and unintended effects of protease inhibitor-expressing plants on non-target organisms. The main intended effect for a recombinant protease inhibitor usually is to provide resistance. In biology and biochemistry, protease inhibitors, or antiproteases, are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins).Many naturally occurring protease inhibitors are proteins.. In medicine, protease inhibitor is often used interchangeably with alpha 1-antitrypsin (A1AT, which is abbreviated PI for this reason).InterPro: IPR Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis se inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles.. Protease inhibitors that have been developed and. The serine protease inhibitors (SPIs) are widely distributed in living organisms like bacteria, fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the proteolytic activity. In plants, most of the studies of SPIs have been focused on their physiological role. The initial studies carried out in plants showed that SPIs participate in the regulation of Cited by: 6.